A 14-year-old boy is evaluated by the physician. His vitals are normal. Laboratory studies are shown:
Hemoglobin 14 g/dL
Leukocytes 7,000/μL
Platelets 250,000/μL
Bleeding time 8 minutes
Prothrombin time 12 seconds
Partial thromboplastin time 50 seconds
Which of the following is the most likely explanation for these findings?
Factor VIII deficiency; Autosomal dominant (AD)
Factor VIII deficiency; Not inherited
Factor VIII deficiency; X-linked recessive (XR)
Impaired platelet aggregation; AD
Impaired platelet aggregation; Not inherited
Impaired platelet aggregation; XR
Impairment of cleavage of vWF multimers; AD
Impairment of cleavage of vWF multimers; Not inherited
Impairment of cleavage of vWF multimers; XR
Paucity of multimeric glycoprotein; AD
Paucity of multimeric glycoprotein; Not inherited
Paucity of multimeric glycoprotein; XR
Vitamin deficiency; AD
Vitamin deficiency; Not inherited
Vitamin deficiency; XR
