HY USMLE Q #1181 – Cardio / Endocrine

A 68-year-old man comes to the physician for a follow-up appointment. He has congestive heart failure managed with enalapril, metoprolol, spironolactone, furosemide, hydralazine, and isosorbide dinitrate. He has type II diabetes mellitus managed with meformin. Laboratory studies are shown:

Sodium                                                                                 130 mEq/L
Potassium                                                                           4.0 mEq/L
Bicarbonate                                                                       24 mEq/L
Calcium                                                                                9.0 mg/dL
BUN                                                                                        20 mg/dL

Which of the following is the most likely explanation for these findings?

  Adverse effect of metformin
  Baroreceptor-mediated ADH release
  Cellular shift
  Prerenal azotemia
  Psychogenic polydipsia