HY USMLE Q #1356 – Pharm / Micro

A 37-year-old woman comes to the physician for a 1-day history of left-sided chest pain, low-grade fever, and mild shortness of breath. She has no past medical history. She works in an office park full-time. Cardiopulmonary examination shows dual heart sounds with no added sounds. Bilateral mild wheezes are heard. A chest x-ray shows interstitial infiltrates bilaterally. Temperature is 101 F. Which of the following is the most appropriate empiric pharmacologic therapy?

  30S inhibitor; can cause otoxicity
  50S inhibitor; can cause grey skin discoloration
  50S inhibitor; can cause gastrointestinal disturbance
  Cell wall synthesis inhibitor; can cause erythroderma
  Folate metabolism inhibitor dual-therapy; can cause neutropenia