A 2-day-old neonatal male is evaluated for persistent jaundice. He was born at term via spontaneous vaginal delivery. Pregnancy was unremarkable. He is slightly lethargic and has scleral icterus. Laboratory studies show low hemoglobin and elevated serum LDH. A blood smear is shown. Which of the following is the most likely explanation for this patient’s findings?
β-globin chain point mutation
Deficiency of UDP-glucuronosyltransferase
Erythrocyte membrane protein deficiency
Glutathione pathway enzyme deficiency
Inhibition of pyrimidine synthesis
Deficiency of UDP-glucuronosyltransferase
Erythrocyte membrane protein deficiency
Glutathione pathway enzyme deficiency
Inhibition of pyrimidine synthesis
