A 32-year-old woman comes to the emergency department with a 3-day history of fever, sore throat, and painful skin lesions. She began taking sulfadiazine and pyrimethamine 1 week ago toxoplasmosis. Over the past 24 hours, she’s developed blistering and epidermal sloughing. Examination shows mucosal involvement of the lips and oral cavity. Around 8% of total body surface area appears involved. She is transferred to a burns unit. Which of the following is the most likely explanation for this patient’s findings?
A) Bullous pemphigoid
B) Epidermolysis bullosa acquisita
C) Pemphigus vulgaris
D) Stevens-Johnson syndrome
E) Toxic epidermal necrolysis
