A 27-year-old woman presents to preconception counseling with her husband. Her family history is remarkable for a sister who died at the age of 6 from cystic fibrosis. Her husband’s family history is unremarkable. If the frequency of disease in the general population is approximately 1 in 40,000 for this condition, what is the probability this couple will have a daughter with the disease?
A) (2/3) x (1/40,000) x (1/4) x (1/2)
B) (2/3) x (1/40,000) x (1/4)
C) (2/3) x (1/200) x (1/4) x (1/2)
D) (2/3) x (1/200) x (1/4)
E) (2/3) x (1/100) x (1/4) x (1/2)
F) (2/3) x (1/100) x (1/4)
G) (3/4) x (1/40,000) x (1/4) x (1/2)
H) (3/4) x (1/40,000) x (1/4)
I) (3/4) x (1/200) x (1/4) x (1/2)
J) (3/4) x (1/200) x (1/4)
K) (3/4) x (1/100) x (1/4) x (1/2)
L) (3/4) x (1/100) x (1/4)
