A 62-year-old woman comes to the emergency department with 3 days of fever, chills, and left-sided flank pain. She also reports dysuria and urinary urgency. Her temperature is 38 C. Physical examination shows left costovertebral angle tenderness. Urinalysis shows positivity for leukocyte esterase, nitrites, and numerous WBCs. She is treated with an agent that is known to cause some ankle problems and cannot be taken with calcium or iron supplements. Which of the following best describes the mechanism of action of the drug she received?
A) 30S ribosomal subunit binding
B) 50S ribosomal subunit binding
C) Cell wall transpeptidase inhibition
D) Dihydrofolate reductase inhibition
E) DNA gyrase inhibition
