A 52-year-old man comes to the physician for a 3-month history of increased thirst, frequent urination, and unintentional weight loss. He has a sedentary lifestyle. BMI is 32. Laboratory studies show a fasting glucose of 148 mg/dL and an HbA1c of 8.2%. Which of the following combinations of enzyme activities is most likely to be seen in this patient?
A) ↑ Glycerol kinase; ↑ Hormone-sensitive lipase; ↑ Glucokinase
B) ↑ Glycerol kinase; ↑ Hormone-sensitive lipase; ↓ Glucokinase
C) ↑ Glycerol kinase; ↓ Hormone-sensitive lipase; ↑ Glucokinase
D) ↑ Glycerol kinase; ↓ Hormone-sensitive lipase; ↓ Glucokinase
E) ↓ Glycerol kinase; ↑ Hormone-sensitive lipase; ↑ Glucokinase
F) ↓ Glycerol kinase; ↑ Hormone-sensitive lipase; ↓ Glucokinase
G) ↓ Glycerol kinase; ↓ Hormone-sensitive lipase; ↑ Glucokinase
H) ↓ Glycerol kinase; ↓ Hormone-sensitive lipase; ↓ Glucokinase
