A 29-year-old man comes to the physician for a 12-hour history of severe abdominal pain that radiates to his back. He has been on the methadone program for 6 months and takes numerous medications. Serum amylase and lipase are 4x the upper limit of normal. Which of the following pharmacologic agents is most likely responsible for this patient’s acute presentation?
A) Didanosine
B) Efavirenz
C) Ritonavir
D) Trimethoprim-sulfamethoxazole
E) Zidovudine

