HY USMLE Q #1470 – Hematology

A 12-year-old girl is brought to the physician for a follow-up appointment. Her father is 49 and has a history of splenectomy and cholecystectomy 20 years ago for an “anemia.” She is asymptomatic. Her vitals are normal.

Which of the following is most likely to be seen in this patient?

A) Direct bilirubin of 2.4 mg/dL
B) Homozygous mutation
C) Mean corpuscular volume of 98 fL
D) Positive direct antiglobulin test
E) Reduced mean corpuscular hemoglobin concentration