A 62-year-old man comes to the physician for a 3-day history of a sore left ankle. He has a history of chronic kidney disease due to granulomatosis with polyangiitis for which he takes prednisone. The agent responsible for this patient’s acute presentation inhibits which of the following, and what condition was he most likely treated for?
A) DNA gyrase; cellulitis
B) DNA gyrase; septic arthritis
C) DNA polymerase; aseptic meningitis
D) DNA polymerase; retinitis
E) Nicking of DNA; pyelonephritis
F) Topoisomerase II; squamous cell carcinoma
