A 15-year-old boy is brought to the physician by his parents for a follow-up examination. His laboratory studies are shown:
Bleeding time 8 minutes
Prothrombin time 14 seconds
Partial thromboplastin time 48 seconds
Platelet count 220,000/μL
Which of the following is the most likely explanation for this patient’s findings?
A) Antibodies against glycoproteins IIb/IIIa
B) Defective glycoprotein IIb/IIIa
C) Deficiency of clotting factor
D) Reduced bridging of glycoprotein Ib to endothelium
E) Reduced cofactor for gamma-glutamyl carboxylase
