HY USMLE Q #1545 – Pathology

A 59-year-old woman comes to the physician for a 1-month history of periodic palpitations, sweating, and the feeling that the room is too hot. She also mentions a slight pulling sensation in the left groin. Menopause occurred at age 52. Vitals are: temperature 99 F, HR 85, RR 14, BP 120/80. A gynecologic ultrasound shows a mass in the left ovary. A biopsy confirms the diagnosis. Which of the following is most likely to be seen in this patient?

A) BRCA1 missense mutation
B) Direct nuclear receptor binding
C) Microinvasion
D) MLH1 missense mutation
E) Pseudomyxoma

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