A 4-year-old boy is brought to the physician by his mother for a high fever and lethargy for the past 24 hours. He has also developed skin lesions on his legs during this time.

Which of the following is most likely to be seen in this patient?
A) Deficiency of adenosine deaminase
B) Deficiency of C1q
C) Deficiency of cell-mediated immunity
D) Deficiency of mucosal immunoglobulin
E) Deficiency of total hemolytic complement

