A 56-year-old woman is brought to the physician by her husband for a 4-month history of progressive cognitive decline. He reports that she’s also had occasional involuntary muscle jerks, usually of the left arm. She has no past medical history apart from a right corneal transplant performed about 2 years ago. Which of the following is most likely to be seen in this patient?
A) Antibodies against aquaporin-4
B) CSF protein 14-3-3
C) Increased alpha-helices
D) Increased PrPc
E) Parkinsonism
