HY USMLE Q #1655 – Hematology

A 48-year-old man comes to the physician for a follow-up appointment. He has a 2-week history of blisters on his forearms that occurred after he took a long bike ride in a park. He has a long history of alcohol consumption and IV drug use. Decreased activity of which of following is the most likely explanation for this patient’s presentation?

A) Delta-aminolevulinic acid dehydratase
B) Delta-aminolevulinic acid synthase
C) Ferrochelatase
D) Porphobilinogen deaminase
E) Uroporphyrinogen decarboxylase

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