A 34-year-old woman comes to the physician for a 2-month history of pain and swelling in her knees and hands, accompanied by morning stiffness that usually lasts one hour. Physical examination shows tenderness and swelling of the metacarpophalangeal joints and knees. Which of the following findings is most likely to develop in this patient over the next ten years?
Decreased FEV1/FVC
Diffuse ST-segment elevations
Mid-systolic click
Paroxysmal supraventricular tachycardia
Soft P2
