HY USMLE Q #635 – Biochemistry / Repro

A 27-year-old woman comes to the physician for a 6-month history of abnormal periods. BMI is 30. Physical examination shows mild acne on the face and shoulders. Which of the following sets of findings is most likely to be seen in this patient?

↑ GLUT4 expression; ↑ Glucokinase activity; ↑ Endometrial cell growth
↑ GLUT4 expression; ↓ Glucokinase activity; ↑ Endometrial cell growth
↑ GLUT4 expression; ↑ Glucokinase activity; ↓ Endometrial cell growth
↑ GLUT4 expression; ↓ Glucokinase activity; ↓ Endometrial cell growth
↓ GLUT4 expression; ↑ Glucokinase activity; ↑ Endometrial cell growth
↓ GLUT4 expression; ↓ Glucokinase activity; ↑ Endometrial cell growth
↓ GLUT4 expression; ↑ Glucokinase activity; ↓ Endometrial cell growth
↓ GLUT4 expression; ↓ Glucokinase activity; ↓ Endometrial cell growth