A 69-year-old woman comes to the physician for a 6-week history of peri-rectal pain that worsens with bowel motions, the latter which she describes as sometimes yellow. She has hypertension, osteoporosis, and psoriasis. Her medications are lisinopril, alendronate, and topical triamcinolone. Vitals are within normal limits. Physical examination shows a draining sinus tract at the anterior perineal wall. Fecal occult blood is positive. Which of the following is most likely to be seen in this patient?
A/B toxin test positivity
Apple core sign
Coffee bean sign
Granulomas
PAS-positive macrophages in the lamina propria
