HY USMLE Q #736 – Heme

A 2-year-old boy is brought to the physician because of increasing lethargy and jaundice over the past two weeks. At birth, he had pathologic jaundice treated with phototherapy. His father had a splenectomy as a child. A 2/6 systolic ejection murmur is auscultated. Hemoglobin is 9.0 g/dL, WBCs 7,000/μL, platelets 200,000/μL, reticulocytes 9%, and total bilirubin 4 mg/dL. A Coombs test is negative. Which of the following is most likely to be seen in this patient?

Antibodies against Rh antigen
Bicuspid aortic valve
Increased lymphoblasts
Normochromic normocytic anemia
Stones (cholesterol)