HY USMLE Q #744 – Heme

A 6-year-old boy is brought to the physician by his mother for a 2-day history of yellow discoloration of his eyes. Hemoglobin is 13 mg/dL. Serum LDH is elevated. A Coombs test is negative. He recovered from an upper respiratory tract viral infection several days ago. A blood smear is shown. Which of the following is most likely to be seen in this patient?

 

 

 

 

 

Decreased activity of glucokinase
Decreased activity of pyruvate kinase
Decreased erythrocyte spectrin
Decreased production of reducing agent
Elevated blood urea nitrogen and thrombocytopenia