A 64-year-old woman comes to the physician for a 6-month history of fatigue, night sweats, and low-grade fever. She has lost 15 pounds during this time. Hemoglobin is 10 g/dL. A colonoscopy is negative. Physical examination shows a palpable left supraclavicular lymph node. Bimanual examination shows adnexal nodularity bilaterally. A biopsy specimen of the left ovary is shown. Which of the following is most likely to be seen in this patient?
Excess liberation of IFN-γ
Hematogenous dissemination
Lamellar body proliferation
Lymphatogenous spread
Mallory hyaline deposition