A 42-year-old woman comes to the physician because of a 3-month history of stiffness and pain in her hands, elbows, and knees. Physical examination shows multiple tender, swollen joints. Hemoglobin is 10.5 g/dL. Serum ferritin is 150 ng/mL. Which of the following antibodies is most likely to support the diagnosis in this patient?
ANCA
Antinuclear
Desmoglein
IgG Fc region
Jo-1
Microsomal
Smooth muscle
