HY USMLE Q #778 – Renal

A 49-year-old woman comes to the physician for a 1-week history of puffiness around her eyes and ankles. She has a history of breast cancer that was managed with lumpectomy and radiation therapy one year ago. A follow-up mammogram 3 months ago showed no recurrences. Serum albumin is 2.5 g/dL. Urinalysis shows 4+ protein and no RBCs. A renal biopsy specimen is shown. Which of the following is the most likely diagnosis?

  Amyloidosis
  Diffuse proliferative glomerulonephritis
  Lipoid nephrosis
  Membranoproliferative glomerulonephritis
 Membranous glomerulonephritis