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A 4-year-old boy is brought to the physician for a 12-hour history of severe pain in his hands. He has a history of a condition in which the beta-chain of his hemoglobin is less hydrophilic than normal. A blood smear is shown. Which of the following is this patient at greatest risk for?
Borellia sepsis
Destruction of platelets due to antibodies against GpIIb/IIIa
Gram-positive diplococcal sepsis
Hemarthrosis
Schistocytosis with thrombocytopenia
