A 25-year-old woman with HIV is brought to the ED by her brother for personality change over the past two weeks. She has had two episodes of Pneumocystis pneumonia during the past year. An MRI of the brain shows multiple ring-enhancing lesions in the frontal and parietal lobes. Which of the following is the most likely explanation for these findings?
Central nervous system demyelination
Central nervous system infection
Metastases
Primary central nervous system lymphoma
Multiple central nervous system infarcts
