HY USMLE Q #895 – Pharm

A 52-year-old woman undergoes a laparoscopic cholecystectomy for acute cholecystitis. The anesthetist administers tubocurarine as part of the induction regimen. Which of the following mechanisms of action is most saliently responsible for the effects of this pharmacologic agent?

  Depolarizing neuromuscular blockade
  GABA potentiation alone
  Nicotinic receptor partial agonism
  Non-depolarizing nicotinic receptor antagonism
  Sodium channel blockade and GABA potentiation