A 26-year-old man is brought to hospital by his girlfriend due to a 1-day history of sense of doom and uneasiness. They both have history of drug use. Vitals are: temperature 103 F, HR 80, RR 16, BP 125/55. Cardiopulmonary auscultation shows an early diastolic murmur broadly at the upper sternal border. Empiric intravenous antibiotic therapy is initiated. Within 48 hours, the patient reports the room is spinning. A pharmacologic agent that inhibits which of the following is most likely responsible for this patient’s acute presentation?
30S
50S
Cell wall synthesis
Dihydrofolate reductase
Topoisomerase II/IV
