A 51-year-old man with HIV is admitted to hospital for a 2-day history of rigors, chills, and high fever. Blood cultures grow Aspergillus. Intravenous caspofungin is initiated. Inhibition of which of the following best explains the efficacy of this pharmacologic agent?
Carbohydrate synthesis
Ergosterol synthesis
Lanosterol synthesis
P-450-mediated demethylation
Tubulin
