HY USMLE Q #934 – Gastro

A 9-year-old girl is brought to the physician by her mother for periodic diarrhea. She has no past medical history. Hemoglobin is 14 g/dL. MCV is 85 fL. A D-xylose test is normal. A duodenal biopsy is shown. Which of the following is the most likely explanation for this patient’s presentation?

  Disaccharidase deficiency
  Exocrine pancreatic insufficiency
  Insensitivity to gliadin
  Milk protein allergy
  PAS-positive macrophage infiltration