A 7-year-old boy is brought to the physician following injuring his knee while playing soccer. Arthrocentesis is positive for blood. Past medical history is unremarkable. He has a maternal uncle who died in childhood from mild head trauma. Impairment of which of the following is most likely responsible for this patient’s presentation?
Antibodies against clotting factor
Clotting factor synthesis
Gamma-carboxylation of clotting factors
Platelet adhesion
Platelet aggregation
