A 46-year-old man is being managed in hospital for a severe autoimmune flare. One year ago he was managed for necrotizing sinusitis. BUN is 200 mg/dL. Creatinine is 7.1 mg/dL. Urinalysis shows 2+ blood and 1+ protein. Physical examination shows a left foot drop and “frost” on the legs, torso, and face. Which of the following is most likely to be seen in this patient?
Anti-cyclic citrullinated peptide antibodies
Anti-dsDNA antibodies
Anti-glomerular basement membrane antibodies
c-ANCA
p-ANCA
