HY USMLE Q #960 – Pathology

A 59-year-old man comes to the physician for his annual low-dose chest CT. He has been smoking one pack of cigarettes daily for 40 years. He has no symptoms. BMI is 24. Vitals are normal. A coin nodule is seen on imaging. A biopsy specimen is shown. Which of the following is most likely to be seen in this patient?

  Decreased urinary specific gravity
  Elevated serum calcium
  Increased osteoclast activity
  Migratory thrombophlebitis
  Post-synaptic antibodies