A 17-year-old boy comes in for a follow-up examination. He has a life-long history of lower respiratory tract infections treated with antibiotics. Childhood was complicated by rickets and failure to thrive. Examination shows clubbing and dusky discoloration of the nailbeds. There is 2+ pedal edema. Which of the following is the most likely explanation for this patient’s edema?
Cardiac amyloidosis
Chronic constrictive pericarditis
Ciliary dyskinesia
Pulmonary edema
Pulmonary hypertension