HY USMLE Q #972 – Pathology

A 25-year-old man comes to the physician for diarrhea for the past 5 months. He has 6-8 greasy, floating stools daily. The diarrhea is worse postprandially. There is no pain, blood, or mucous in the stool. He has type I diabetes mellitus. Vitals are normal. Laboratory studies show:

Hemoglobin                                                                                                 10 g/dL
MCV                                                                                                                 72 fL
Leukocytes                                                                                                    7,000/μL
Platelets                                                                                                          300,000/μL

Which of the following is the most likely explanation for this patient’s findings?

  Gastrointestinal dysmotility
  Invasion with actin polymerization
  Osmotic effect
  Small bowel villous atrophy
  Transmural caseating granulomatous inflammation