A 32-year-old woman comes to the physician for a 2-month history of vaginal bleeding between menses. Her cycles have always occurred at regular, 28-day intervals. Serum and laboratory studies are within normal limits. Thyroid-stimulating hormone is not elevated. She has a 36-year-old brother who was recently diagnosed with colon cancer. Which of the following is most likely to be seen in this patient’s condition?
Defective recombinational double-stranded DNA repair
Constitutive GTPase activity
Increased production of anti-apoptotic molecule
Microsatellite instability
Transcription factor upregulation
