A 32-year-old man comes to the physician for evaluation of recurrent episodes of bronchitis and sinusitis throughout his life. Cardiac examination shows a point of maximal impulse at the 4th intercostal space on the right. There is large mass palpable beneath the costal margin on the left. Endosccopy shows nasal polyps. Which of the following is the most likely explanation for these findings?
Chloride channel
Dynein
Gap junction
Lysosome
Microtubule
Peroxisome