HY USMLE Q #726 – Biochemistry

A 62-year-old man comes to the physician for a 6-month history of fatigue. Colonoscopy reveals a tumorigenic lesion. Biopsy and molecular analysis shows lack of GTPase activity of G-α-s G-proteins. Which of the following is most likely to be seen on further analysis of the tumor cells?

↑ cAMP
↑ cGMP
↑ IP3
  cAMP
↓ cGMP
↓ IP3