HY USMLE Q #1088 – Repro / Biochem

A 28-year-old man comes to the physician with his wife because of a 1-year history of inability to conceive. His wife has two children with a prior partner. He has a history of sporadic bacterial pneumonias treated successfully with antibiotics. He is a non-smoker and non-drinker. BMI is 25. Vitals are normal. A chest x-ray is shown. Which of the following is most likely to be seen in this patient?

  Congenital bilateral absence of vas deferens
  Cytoskeletal motor protein dysfunction
  Decreased androgen-binding protein
  Increased follicle-stimulating hormone
  Misfolded protein sequestered in rough endoplasmic reticulum

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