HY USMLE Q #1138 – Endocrine / Biochemistry

An 8-year-old girl is brought to emergency by her mother for a 1-day history of severe drowsiness and confusion. For the past one week, she has had increased urination, thirst, and slight visual blurring. Two weeks ago, she recovered from a flu-like illness. She is afebrile. Which of the following combinations of findings is most likely to be seen in this patient?

  ↑ Glucokinase activity; ↑ Bicarb; ↑ pCO2; ↑ Serum potassium
  ↑ Glucokinase activity; ↑ Bicarb; ↑ pCO2; ↓ Serum potassium
  ↑ Glucokinase activity; ↑ Bicarb; ↓ pCO2; ↑ Serum potassium
  ↑ Glucokinase activity; ↑ Bicarb; ↓ pCO2; ↓ Serum potassium
  ↑ Glucokinase activity; ↓ Bicarb; ↑ pCO2; ↑ Serum potassium
  ↑ Glucokinase activity; ↓ Bicarb; ↑ pCO2; ↓ Serum potassium
  ↑ Glucokinase activity; ↓ Bicarb; ↓ pCO2; ↑ Serum potassium
  ↑ Glucokinase activity; ↓ Bicarb; ↓ pCO2; ↓ Serum potassium
  ↓ Glucokinase activity; ↑ Bicarb; ↑ pCO2; ↑ Serum potassium
  ↓ Glucokinase activity; ↑ Bicarb; ↑ pCO2; ↓ Serum potassium
  ↓ Glucokinase activity; ↑ Bicarb; ↓ pCO2; ↑ Serum potassium
  ↓ Glucokinase activity; ↑ Bicarb; ↓ pCO2; ↓ Serum potassium
  ↓ Glucokinase activity; ↓ Bicarb; ↑ pCO2; ↑ Serum potassium
  ↓ Glucokinase activity; ↓ Bicarb; ↑ pCO2; ↓ Serum potassium
  ↓ Glucokinase activity; ↓ Bicarb; ↓ pCO2; ↑ Serum potassium
  ↓ Glucokinase activity; ↓ Bicarb; ↓ pCO2; ↓ Serum potassium

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