A 50-year-old woman comes to the physician for a 4-month history of fatigue, itchiness of the trunk and back, and yellowish discoloration of her eyes. Serum cholesterol is elevated. She had an episode of subacute granulomatous thyroiditis 2 years ago. Vitals are normal. Pancreatic amylase and lipase are normal. Which of the following is most likely to be seen in this patient?
Decreased biliary peristalsis
Increased cholesterol secretion into bile
Oxalate urolithiasis
Production of antibodies against organellar protein
Sphincter of Oddi dysfunction
